The effect of nonsense codons on splicing: a genomic analysis.
نویسندگان
چکیده
The phenomenon of nonsense-associated altered splicing raises the possibility that the recognition of in-frame nonsense codons is used generally for exon identification during pre-mRNA splicing. However, nonsense codon frequencies in pseudo exons and in regions flanking 5' splice sites are no greater than that expected by chance, arguing against the widespread use of this strategy as a means of rejecting potential splice sites.
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عنوان ژورنال:
- RNA
دوره 9 6 شماره
صفحات -
تاریخ انتشار 2003